DEVONIAN HEALTH GROUP OBTAINS CANNABIS RESEARCH LICENSE FROM HEALTH CANADA.

QUEBEC, October 3, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation”) (TSXv: GSD), a clinical stage botanical pharmaceutical corporation focused on developing a unique portfolio of botanical prescription drugs and cosmeceutical products, announced today that it has obtained, from Health Canada, a Research licence pursuant to the Cannabis Act and Cannabis Regulations.

The licence gives Devonian the ability to begin its pharmaceutical cannabis research program at its facility in Montmagny, Quebec. The licence also includes satellite research sites located at the laboratories of Dr Suha Jabaji, PhD (Department of Plant Science, McGill University) and Dr Louis Flamand, PhD, MBA (Department of Microbiology and Immunology, Laval University).

“We can now initiate our cannabinoids-based pharmaceutical program with the vision that such products could be developed under the US-Food and Administration’s Botanical Drug Regulation¹. The US Food and Drug Administration (FDA) established a clear regulatory pathway for botanical drugs. The US FDA’s botanical path considers a plant extract to be a drug. The rationale behind this regulatory approach is that the observed efficacy of such extract has been associated with the action of multiple components including any synergistic effects also called the ‘‘entourage effects’’. Botanical drug development therefore involves methods that allow the isolation and characterisation of synergistic bioactive components and plays a significant role in sustaining efficacy of this class of drugs. Devonian’s core strategy is to develop prescription drugs, including those based on cannabinoids, within the Botanical Drug Regulatory pathway.,” said Dr. André P. Boulet, PhD., President & CEO of Devonian.

About Devonian

Devonian Health Group Inc. is a late stage botanical pharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings.  Devonian Health Group Inc. was incorporated in 2015 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercialization partner, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSXV Exchange (TSXv:GSD).

For more information, visit www.groupedevonian.com.

Reference

1. Botanical Drug Development, Guidance for Industry. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), December 2016.

Forward Looking Statements

This press release contains forward-looking statements about Devonian’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate. Such risks and assumptions include, but are not limited to, Devonian’s ability to develop, manufacture, and successfully commercialize value-added pharmaceutical and dermo-cosmeceutical products, the availability of funds and resources to pursue R&D projects, the successful and timely completion of clinical studies, the ability of Devonian to take advantage of business opportunities in the pharmaceutical and dermo-cosmeceutical industries, uncertainties related to the regulatory process and general changes in economic conditions. You will find a more detailed assessment of the risks that could cause actual events or results to materially differ from our current expectations in Devonian’s prospectus dated April 21^st, 2017 under the heading “Risk Factors” related to Devonian’s business. As a result, we cannot guarantee that any forward-looking statement will materialize. We assume no obligation to update any forward-looking statement even if new information becomes available, as a result of future events or for any other reason, unless required by applicable securities laws and regulations.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post Devonian Health Group Obtains Cannabis Research License from Health Canada appeared first on DEVONIAN HEALTH GROUP INC..

Devonian Health Group Announces the Formation of a Clinical Dermatology Advisory Board with mandate to assist in the development of Cannabinoids-based pharmaceutical products.

QUEBEC, September 4, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation”) (TSXv: GSD), a clinical stage botanical pharmaceutical corporation focused on developing a unique portfolio of botanical prescription drugs and cosmeceutical products, announced today that it has formed a Clinical Dermatology Advisory Board comprised of Canadian Key Opinion Leaders.  The objective of the Clinical Dermatology Advisory Board is to provide clinical, scientific, research and strategic guidance to the Corporation as it continues to advance its pharmaceutical cannabis product development.

The appointees are Drs Sam Hanna, MD, FAAD, DABD; Ian Landells, MD, FRCPC; Jaggi Rao, MD, FRCPC and Jerry Tann, MD, FRCPC.

“We are honored to welcome these Canadian Key Opinion Leaders to our newly established Clinical Dermatology Advisory Board. The expertise they bring to our team will be instrumental in guiding us through the development of cannabinoids-based pharmaceutical drugs within our ongoing dermatology drug development program,” said Dr. André P. Boulet, PhD., President & CEO of Devonian.

“We believe that cannabinoids-based products could be developed under the US-Food and Administration’s Botanical Drug Regulation¹. Under this regulation, plant active ingredients, like those in cannabinoids-based products, benefit of the combined effects of the components called the ‘‘entourage effects’’. Devonian’s core strategy is to develop drugs, including those based on cannabinoids, within the Botanical Drug Regulatory pathway.,” added Dr Boulet.

Sam HANNA, MD, FAAD, DABD

Dr. Hanna trained in medicine and completed specialty training and board certification in the US before returning home to Canada.  As the clinic director of a large single specialty dermatology group in downtown Toronto, Dr. Hanna enjoys his “blended” dermatology practice combining Aesthetic, Medical and Investigational Dermatology.

Dr. Hanna is past secretary of the Canadian Dermatology Association’s Board of Directors and sits on the CDA Membership and Awards Committee as well as the Pharmacy & Therapeutics committee.  He is the immediate past President of the Toronto Dermatological society.  He is a member of the Dermatology Association of Ontario and of the American Academy of Dermatology. Dr. Hanna Received the CDA President’s Cup award for volunteerism in Dermatology in 2016. His research interest is in cosmetic dermatology, psoriasis, atopic dermatitis, acne and rosacea.

Ian D. R. LANDELLS, MD, FRCPC

Dr. Ian Landells graduated from Memorial University of Newfoundland Medical School in 1988. Practiced two years Family Medicine in St. John’s, NL, then went on to study Paediatric Medicine at Memorial University, and Dermatology at the University of British Columbia. He graduated from University of British Columbia in 1995 and went on to do a fellowship training in Paediatric Dermatology at Northwestern University and Children’s Memorial Hospital in Chicago, IL, USA. Dr. Landells practiced Adult and Paediatric Dermatology in St. John’s, NL since 1996. He is currently Division Chief Dermatology at Eastern Health, Clinical Associate Professor, Disciplines of Medicine and Paediatrics-Faculty of Medicine, Memorial University of Newfoundland, and Medical Director Dermatology at Nexus Clinical Research, St. John’s, NL. Dr Landells was President (2010-2011) and Past Vice-President, Secretary and Regional Director of the Canadian Dermatology Association. He also was President (2003-2004) of the Atlantic Provinces Dermatology Association. He is a member of the Editorial Boards of the International Journal of Dermatology, the Journal of Cutaneous Medicine and Surgery, Dermatology Times of Canada, Journal of Cosmetic Dermatology and Latin American Journal of Psoriasis and Psoriatic Arthritis. He has participated in over 100 clinical trials.

Jaggi RAO, MD, FRCPC

Dr. Jaggi Rao is a double board certified dermatologist (Canada and USA) and a certified cosmetic surgeon. In 1995, he received a Bachelor of Science (BSc) degree with high distinction from the University of Toronto, followed by his Doctorate of Medicine (MD) from McMaster University in 1998. He then completed his 5-year specialty training in dermatology at the University of Alberta. This was followed by the completion of an accredited fellowship with the American Academy of Cosmetic Surgery in Southern California. Dr. Rao is a full Clinical Professor of Medicine and served as the Program Director for the Dermatology Residency Training Program at the University of Alberta from 2009 to 2014.
Dr. Rao has won several accolades for writing, presentations, research and teaching, including the Canadian Dermatology Association’s Teacher of the Year Award. In 2011, he was the recipient of Avenue Magazine’s Top 40 under 40 Award. He has authored over 50 scientific papers and textbook chapters and has been an invited speaker for over 500 lectures worldwide to physicians, other professionals, industry and the general public. Dr. Rao is a popular instructor for a number of dermatology-related courses and educational projects. He continues to lend his expertise as a consultant to various organizations including the government (such as the Canadian Standards Association), medical device and pharmaceutical industry, healthcare provision businesses, and professional sports teams.

Clinically, Dr. Rao has been a practicing dermatologist for over 10 years, and is the founder of the Rao Dermatology Centre, a popular medical & cosmetic derma surgery facility in the heart of Edmonton, Alberta. He has developed several innovative treatment protocols and techniques that have been adopted by other healthcare professionals. Dr. Rao is the creator and visionary behind ConsultDERM™, Canada’s largest teledermatology service, which uses modern technologies to allow healthcare providers gain timely access, regardless of distance or location, to dermatology assistance for patients with skin-related problems. Dr. Rao continues to volunteer with Doctors Without Borders (MSF) and the Canadian Physicians for Aid & Relief (CPAR).

Jerry Tan MD FRCPC Dermatology

Dr. Tan trained in internal medicine at the University of Toronto and in dermatology at University of British Columbia and University of Michigan. He has a general dermatology and aesthetic practice in Windsor Ontario Canada since 1991 and conducts research with Windsor Clinical Research, a clinical trials site in dermatology. Areas of research include acne, rosacea, hidradenitis suppurativa. Additional interests include dermatology outcome measurements and aesthetic dermatology including scar correction. He is the chair of the working group on clinical practice guidelines of the Canadian Dermatology Association and co-chair of the rosacea international consensus group (ROSCO) and the acne core outcomes network (ACORN).

About Devonian

Devonian Health Group Inc. is a late stage botanical pharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings.  Devonian Health Group Inc. was incorporated in 2015 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercialization partner, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSXV Exchange (TSXv:GSD).

For more information, visit www.groupedevonian.com.

References

1. Botanical Drug Development, Guidance for Industry. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), December 2016.

Forward Looking Statements

This press release contains forward-looking statements about Devonian’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate. Such risks and assumptions include, but are not limited to, Devonian’s ability to develop, manufacture, and successfully commercialize value-added pharmaceutical and dermo-cosmeceutical products, the availability of funds and resources to pursue R&D projects, the successful and timely completion of clinical studies, the ability of Devonian to take advantage of business opportunities in the pharmaceutical and dermo-cosmeceutical industries, uncertainties related to the regulatory process and general changes in economic conditions. You will find a more detailed assessment of the risks that could cause actual events or results to materially differ from our current expectations in Devonian’s prospectus dated April 21^st, 2017 under the heading “Risk Factors” related to Devonian’s business. As a result, we cannot guarantee that any forward-looking statement will materialize. We assume no obligation to update any forward-looking statement even if new information becomes available, as a result of future events or for any other reason, unless required by applicable securities laws and regulations.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post Devonian Health Group Announces the Formation of a Clinical Dermatology Advisory Board with mandate to assist in the development of Cannabinoids-based pharmaceutical products appeared first on DEVONIAN HEALTH GROUP INC..

Devonian Health Group announces the publication of positive results of the Purgenesis^® Anti-aging Care clinical study in the Journal of Cosmetic Dermatology.

QUEBEC, August 28, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation”) (TSXV: GSD), a clinical stage botanical pharmaceutical corporation focused on developing a unique portfolio of botanical prescription drugs and cosmeceutical products, announced today the publication of positive results from the comparative clinical study on Purgenesis® Anti-aging Care in the management of lateral canthal lines (Crow’s feet).

Published in the peer-reviewed Journal of Cosmetic Dermatology¹ and titled ‘‘Comparison of topical antiaging creams in the management of lateral canthal lines’’, the article describes results from a clinical study comparing the efficacy of Purgenesis® antiaging creams ( Day cream, Eye Cream and Night Cream) to Prevage^® (Eye Lotion, Day Cream and Night Cream) and to LaMer^® ( Eye Balm, Crème de la Mer and Night Cream) in the management of lateral canthal lines.

This single-center, single-blind, parallel-design clinical study enrolled 72 healthy female volunteers, aged 35 to 72 years, with fine-to-moderate wrinkles in the lateral canthal areas (crow feet). Assessments were conducted over 28 days and included skin hydration, cutaneous elasticity, profilometry (anti-wrinkle effect) and satisfaction survey (volunteers’ perception of their treatment).  Results showed that volunteers using the Purgenesis^® Anti-aging Care line experienced more statistically significant improvements in objective measures than seen with the two other product lines. These improvements include skin hydration, extensibility, fatigability, firmness, and effects on wrinkles (total number, area and total length of wrinkles).  All treatments were well tolerated by the majority of the participants.

“What intrigues me about Purgenesis® is that it’s a Canadian made, naturally sourced botanical, backed by science. When I recommend it to patients, I emphasize the fact that it is an anti-aging treatment system, not just a moisturizer. I am very impressed that Devonian had the faith in their product to test it head-to-head against leading brands. The results were quite interesting, with Purgenesis^® coming out on top.”, said Dr. Julia M. Carroll BSC, MD, FRCP, Director and Co-Founder of Compass Dermatology; Director of Dermatology, The Medcan Clinic. Toronto, Ontario.

“Effective antioxidants are a cornerstone of the skin care regimens I recommend to my patients. Purgenesis® and its primary active ingredient, R-Spinosome®, outperformed two existing market-leading antioxidants. The properties documented in this paper clearly demonstrate that Purgenesis^® is an excellent choice for people looking for a cosmetically elegant, total antioxidant solution for the face, neck and eyes.”, said Dr. Sam Hanna MD, FAAD, DABD, Medical Director, Dermatology on Bloor; President, Toronto Dermatology Society, Toronto, Ontario.

“We are very pleased to announce this scientific publication describing the efficacy of Purgenesis^® Anti-aging Care line. The data from this clinical study highlights the efficacy and faster onset of action of Purgenesis^®, as seen by a statistical reduction of the total number of wrinkles after only one day of treatment, compared to Prevage^® and LaMer^®. We look forward to evaluate the longer-term effects of our products in a future clinical trial.”, says Devonian’s President & CEO, Dr. Andre P. Boulet, PhD.

 “With this recent publication, Purgenesis® is well positioned to respond to the increasing and discerning demand for evidence-based skincare products. Purgenesis® is exclusively available from dermatologists, plastic surgeons and medical spas, and for good reason. Who else but medically trained skin care experts can appreciate the decades of research that has given life to the active complex R-Spinasome^®. This is what forms the basis of Purgenesis® and the reason why our science-based, clinically proven formulations are chosen by experts as the daily skincare solution for women and men of all skin types.”, says Sybil Dahan, President of Altius Healthcare, Devonian’s Commercial Division,

About Purgenesis® Anti-aging Care treatment

Purgenesis® Anti-aging Care treatment has three components: a day cream, a night cream and an eye cream. These creams contain R-Spinasome®, a complex that is an active structure with anti-oxidant properties. The structure of this complex is critical to its function as an anti-oxidant, enabling it to capture and dissipate noxious energy generated by Reactive Oxygen Species (ROS), returning the complex to a state where it is ready to undergo new activation cycles. It is this dynamism and capacity to regenerate that provides R-Spinasome^® with unprecedented, long-lasting antioxidant activity. Purgenesis® Anti-aging treatment is patent protected in Japan, Canada, United States and Europe (#JP 5952261; #CDN 2,699,6765; #US 13/261,472, #EUR 11 768 299.7). The product has been recognized by the Canadian Dermatology Association’s Skin Health Program™.

About Devonian

Devonian Health Group Inc. is a late stage botanical pharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings.  Devonian Health Group Inc. was incorporated in 2013 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercialization partner, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSXV Exchange (TSXv:GSD).

For more information, visit www.groupedevonian.com.

About Altius Healthcare Inc.

Based in Concord, Ontario, Altius Healthcare is a specialty pharmaceutical company with a primary focus of acquiring and in-licensing safe and innovative medicines and healthcare products designed to help people of all ages live healthier lives. Altius then leverages its expertise in the commercialisation activities required to successfully launch and distribute these medicines in Canada. The team’s diverse experience and expertise draws from nearly 40 years of producing, importing, marketing and distributing branded and generic medicines.

For more information, visit www.altiushealthcare.ca

Reference

Carroll, JM; Guenther, LC; Hanna, S and N Boucher, Comparison of topical antiaging creams in the management of lateral canthal lines. J. Cosmet. Dermatol. 2019; 00:1-11

Forward Looking Statements

This press release contains forward-looking statements about Devonian’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate. Such risks and assumptions include, but are not limited to, Devonian’s ability to develop, manufacture, and successfully commercialize value-added pharmaceutical and cosmeceutical products, the availability of funds and resources to pursue R&D projects, the successful and timely completion of clinical studies, the ability of Devonian to take advantage of business opportunities in the pharmaceutical and cosmeceutical industries, uncertainties related to the regulatory process and general changes in economic conditions. You will find a more detailed assessment of the risks that could cause actual events or results to materially differ from our current expectations in Devonian’s prospectus dated April 21^st, 2017 under the heading “Risk Factors” related to Devonian’s business. As a result, we cannot guarantee that any forward-looking statement will materialize. We assume no obligation to update any forward-looking statement even if new information becomes available, as a result of future events or for any other reason, unless required by applicable securities laws and regulations.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post Devonian Health Group announces the publication of positive results of the Purgenesis® Anti-aging Care clinical study in the Journal of Cosmetic Dermatology appeared first on DEVONIAN HEALTH GROUP INC..

DEVONIAN ANNOUNCES THE CLOSING OF A $315,000 PRIVATE PLACEMENT AND AN ADDITIONAL LOAN OF $500,000

QUEBEC, Québec – August 21, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation”) (TSXv: GSD) is pleased to announce the closing of a non-brokered private placement (the “Offering”) of 1,260,000 units of the Corporation (the “Units”), at a price of $0.25 per Unit, for an aggregate gross proceeds of $315,000. Each Unit subscribed for under the Offering is comprised of one subordinate voting shares of the Corporation (a “Subordinate Voting Share”) and one-half of one Subordinate Voting Share purchase warrant (a “Purchase Warrant”). Each whole Purchase Warrant shall entitle the holder thereof to subscribe for one Subordinate Voting Shares of the Corporation, at a price of $0.50 per Subordinate Voting Share, for a period of 24 months following the closing of the Offering, subject to acceleration provision.

The Corporation paid Raymond James Ltd. an intermediation fees in the amount of $15,900 and an aggregate number of 63,600 compensation warrants to purchase of up to 63,600 Subordinate Voting Shares, at a price of $1.00 per Subordinate Voting Share, within a delay of 24 months after the closing of the Offering, subject to acceleration provision.

The net proceeds of the Offering will be used by the Corporation for working capital and general corporate purposes.

The Corporation may proceed with subsequent closings up to a maximum cumulative aggregate gross proceeds of $5,000,000.

All securities issued under the Offering are subject to a four month and one day hold period from the date of issue in accordance with applicable securities laws expiring on December 22, 2019.

Additional Loan

The Corporation is pleased to announce that it has concluded an amendment to the loan agreement previously announced on January 23, 2019, entered into with a Private Group of Lenders (the “Loan Agreement”) in order to increase the maximum of the loan from $3,000,000 to $3,500,000. This additional loan falls under the same terms provided under the Loan Agreement being understood that the $500,000 may be reimbursed by the Corporation at any time without penalty.

This press release does not constitute an offer of securities for sale in the United States or to “U.S. persons” (“U.S. persons”), as such term is defined in Regulation S promulgated under the United States Securities Act of 1933, as amended (the “U.S. Securities Act”). The securities being offered have not been, nor will be, registered under the U.S. Securities Act or any state securities laws, and may not be offered or sold in the United States or to U.S. persons absent registration or an applicable exemption from such registration requirements.

About Devonian

Devonian Health Group Inc. is a late stage biopharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings. Devonian Health Group Inc. was incorporated in 2013 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercial division, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSX Exchange (TSXV:GSD).

For more information, visit www.groupedevonian.com.

Forward Looking Statements

All statements, other than statements of historical fact, contained in this press release including, but not limited to, those relating to the intended use of proceeds of the Offering, and generally, the above “About Devonian” paragraph which essentially describes the Corporation’s outlook, constitute “forward-looking information” or “forward-looking statements” within the meaning of certain securities laws, and are based on expectations, estimates and projections as of the time of this press release. Forward-looking statements are necessarily based upon a number of estimates and assumptions that, while considered reasonable by the Corporation as of the time of such statements, are inherently subject to significant business, economic and competitive uncertainties and contingencies. These estimates and assumptions may prove to be incorrect. Many of these uncertainties and contingencies can directly or indirectly affect, and could cause, actual results to differ materially from those expressed or implied in any forward-looking statements and future events.

By their very nature, forward-looking statements involve inherent risks and uncertainties, both general and specific, and risks exist that estimates, forecasts, projections and other forward-looking statements will not be achieved or that assumptions do not reflect future experience. Forward-looking statements are provided for the purpose of providing information about management’s endeavors to develop prescription botanical drugs and, more generally, its expectations and plans relating to the future. Readers are cautioned not to place undue reliance on these forward-looking statements as a number of important risk factors and future events could cause the actual outcomes to differ materially from the beliefs, plans, objectives, expectations, anticipations, estimates, assumptions and intentions expressed in such forward-looking statements. All of the forward-looking statements made in this press release are qualified by these cautionary statements and those made in our other filings with the securities regulators of Canada. The Corporation disclaims any intention or obligation to update or revise any forward-looking statements or to explain any material difference between subsequent actual events and such forward-looking statements, except to the extent required by applicable law.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post DEVONIAN ANNOUNCES THE CLOSING OF A $315,000 PRIVATE PLACEMENT AND AN ADDITIONAL LOAN OF $500,000 appeared first on DEVONIAN HEALTH GROUP INC..

Dr George G. Zhanel joins Devonian’s Cannabinoids Scientific Advisory board.

Quebec – July 23, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation“) (TSXv: GSD), a clinical stage biopharmaceutical corporation focused on developing a unique portfolio of botanical prescription drugs and cosmeceutical products, today announces that Professor George G. Zhanel has joined the Corporation’s Scientific Advisory Board for its Cannabinoids-based pharmaceutical program.

Dr. Zhanel received his Ph.D. in the Department of Medical Microbiology/Infectious Diseases at the Faculty of Medicine, University of Manitoba and a Doctor of Clinical Pharmacy at the University of Minnesota. He is presently Professor in the Department of Medical Microbiology/Infectious Diseases, College of Medicine; Course Leader, Infectious Diseases Teaching, College of Medicine, University of Manitoba; Coordinator of Antibiotic Resistance in the Departments of Medicine and Clinical Microbiology, Health Sciences Centre;  and Research Director of the Canadian Antimicrobial Resistance Alliance (CARA). Dr Zhanel is the founding and Chief Editor of the Canadian Antimicrobial Resistance Alliance (CARA) website (www.can-r.ca).

Dr. Zhanel has published over 1000 papers, chapters and abstracts in the area of antimicrobial resistant infections. He has presented over 1000 lectures as an invited speaker at international, national, and local meetings speaking on the topics of antimicrobial resistant infections as well as treatment and prevention of infectious diseases in Canada, United States, Central and South America, Western and Eastern Europe including Russia, Australia, Southern and Northern Africa, the Middle East and Asia.

Professor Zhanel commented, “I am really excited to join the scientific board to bring value to the cannabinoids-based pharmaceutical program”.

“Professor Zhanel is known globally both for his extensive research in the field of Infectiology. We are delighted that he has agreed to join our Scientific Advisory Board. With his unique experience in the field of Infectious Diseases, we are confident the Professor Zhanel will be able to make a significant contribution to our cannabinoids-based pharmaceutical program “, said Dr Andre P. Boulet, President and Chief Executive Officer of Devonian.

About Devonian

Devonian Health Group Inc. is a late stage biopharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings.  Devonian Health Group Inc. was incorporated in 2013 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercial division, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSX Exchange (TSXv:GSD).

For more information, visit www.groupedevonian.com.

Forward Looking Statements
This press release contains forward-looking statements about Devonian’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate. Such risks and assumptions include, but are not limited to, Devonian’s ability to develop, manufacture, and successfully commercialize value-added pharmaceutical and cosmeceutical products, the availability of funds and resources to pursue R&D projects, the successful and timely completion of clinical studies, the ability of Devonian to take advantage of business opportunities in the pharmaceutical and cosmeceutical industries, uncertainties related to the regulatory process and general changes in economic conditions. You will find a more detailed assessment of the risks that could cause actual events or results to materially differ from our current expectations in Devonian’s prospectus dated April 21, 2017 under the heading “Risk Factors” related to Devonian’s business. As a result, we cannot guarantee that any forward-looking statement will materialize. We assume no obligation to update any forward-looking statement even if new information becomes available, as a result of future events or for any other reason, unless required by applicable securities laws and regulations.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post Dr George G. Zhanel joins Devonian’s Cannabinoids Scientific Advisory board appeared first on DEVONIAN HEALTH GROUP INC..

Devonian Announces the Filing of a New Patent Application related to use of Thylakoids as delivery system for Cannabinoïds and other Liposoluble Molecules.

Quebec – June 5, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation“) (TSXv: GSD), a clinical stage biopharmaceutical corporation, today announced that the Corporation has filed a patent application for the use of thylakoids as delivery system for cannabinoids and other liposoluble molecules for pharmaceutical and cosmetic applications.

The patent application relates to thylakoids and functional derivatives, as carriers for molecules. More specifically, this invention relates to a composition comprising functional thylakoids, particularly in specific formulations that ensure the integrity and functionality of molecules, particularly liposoluble molecules, that are difficult to formulate, to increase their bioavailability. The patent covers the extraction of cannabinoids-containing thylakoids from plant such as Cannabis sativa, indica or hemp. It also covers the incorporation of liposoluble molecules, such as cannabinoids, into thylakoids extracted from any photosynthetic organism.

“The filing of this new patent is another pivotal component of our broad strategy of expanding our already list of patents. Importantly, this filing is timely as we look to demonstrate the potential broad application of our technology. Furthermore, this new patent aligns to our pharmaceutical cannabinoids-based drug development program.” said Dr. André P. Boulet, President & CEO of Devonian.

About Devonian

Devonian Health Group Inc. is a late stage biopharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings.  Devonian Health Group Inc. was incorporated in 2013 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercial division, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSX Exchange (TSXv:GSD).

For more information, visit www.groupedevonian.com.

Forward Looking Statements

This press release contains forward-looking statements about Devonian’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate. Such risks and assumptions include, but are not limited to, Devonian’s ability to develop, manufacture, and successfully commercialize value-added pharmaceutical and cosmeceutical products, the availability of funds and resources to pursue R&D projects, the successful and timely completion of clinical studies, the ability of Devonian to take advantage of business opportunities in the pharmaceutical and cosmeceutical industries, uncertainties related to the regulatory process and general changes in economic conditions. You will find a more detailed assessment of the risks that could cause actual events or results to materially differ from our current expectations in Devonian’s prospectus dated April 21, 2017 under the heading “Risk Factors” related to Devonian’s business. As a result, we cannot guarantee that any forward-looking statement will materialize. We assume no obligation to update any forward-looking statement even if new information becomes available, as a result of future events or for any other reason, unless required by applicable securities laws and regulations.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post Devonian Announces the Filing of a New Patent Application related to use of Thylakoids as delivery system for Cannabinoïds and other Liposoluble Molecules appeared first on DEVONIAN HEALTH GROUP INC..

Devonian signs a Binding Letter of Intent with Histapharm Inc. to extract and manufacture their proprietary botanical pharmaceutical product and to enter into a Strategic Partnership for the development of New Products.

Quebec – June 3, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation“) (TSXv: GSD), , a clinical stage biopharmaceutical corporation focused on developing a unique portfolio of botanical prescription drugs and cosmeceutical products, and Histapharm Inc. (‘‘Histapharm’’), a company pioneering the control of histamine level in various dysfunctions, announced today that they have signed a binding Letter of Intent (‘‘LOI’’) to negotiate the terms establishing Devonian as the exclusive site for the extraction and manufacturing of Histapharm’s proprietary botanical drug. Histapharm’s product targets the degradation of histamine being a different approach compared to treatments using antihistamine technologies. The LOI also includes the set-up of a Strategic Partnership focused on the development of new products for dermatological applications.

Under the LOI, Devonian will be the exclusive site for the extraction and manufacturing of the botanical drug containing diamine oxydase (DAO). Furthermore, under the Strategic Partnership, Devonian and Histapharm will develop new products, derived from the combination of their respective platforms, products and know-how.  In order to facilitate the Partnership, Histapharm intends to set up its head office in close proximity to Devonian. The Manufacturing Agreement must be executed within the next 150 days and the Strategic Partnership by November, 30, 2019.

“We are pleased to leverage our R&D and manufacturing assets. By finding a reliable partner, Devonian expects not only to increase its revenues, but also to further focus on its core expertise and strength, that is the development of botanical prescription drugs with a strong franchise in dermatology. The Strategic Partnership with Histapharm will add another Active Botanical Ingredient (ABI) to our pipeline for the development, approval and commercialization of novel products within the dermatology therapeutic area.” said Dr Andre P. Boulet, President and Chief Executive Officer of Devonian.

“Access to Devonian facilities will allow Histapharm to be the first worldwide producer of vegetable-based diamine oxidase in a powder format, positioning Histapharm in a niche market covered and protected by our intellectual properties”. said Guy Bilodeau, President and Chief Executive Officer of Histapharm.

About the transaction

The completion of the definitive agreements is subject to additional conditions, including but not limited to various board of directors’ approvals of Devonian and Histapharm, as well as third party’s consents on terms satisfactory to Devonian and Histapharm and certain other usual conditions. The completion of the definitive agreements is subject to the approval of the TSX Venture Exchange and all other necessary regulatory approvals. There can be no assurance that the transaction will be completed as proposed or at all.

Update on interest settlement announced on March 29, 2019

The Corporation has, by press release dated March 29, 2019, announced the payment of accrued and unpaid interest on convertible debentures issued and outstanding by the issuance of subordinate voting shares (the “Shares”) and units.

Aspri Pharma Inc., an insider of the Corporation, had received only Shares, unlike other subscribers who received units consisting of Shares and Warrants. In the interest of fairness, the Corporation has filed an application for exemption with the TSX Venture Exchange (the “Exchange”) in order for Aspri Pharma Inc. to also obtain warrants. The Exchange has agreed to grant the exemption. As a result, the Company issued 173,831 warrants to Aspri Pharma Inc. Each warrant entitles its holder to subscribe one Share at a price of $ 0.38 per Share on or before April 23, 2021.

About Histapharm Inc.

Histapharm is a Canadian company pioneering the control of histamine level in various dysfunctions by oral administration of the plant enzyme – histaminase (called also Diamineoxidase DAO). This enzymatic botanical drug therapy consists in reducing inflammation through degradation of histamine and hydrogen peroxide. The enzyme-containing product can prevent exacerbation of symptoms related to various dysfunctions linked to histamine excess (mastocytosis, histaminosis) or to inhibition of DAO (i.e. diabetes). Considering the actual high unmet needs, Histapharm is developing the first botanical enzymatic product for people living for many years with symptoms which become worst with disease progression. Histamine is a trigger factor in dysfunctions for which patients are recommended long-life a low-histamine diet and medication including anti-histaminic drugs.

About Devonian

Devonian Health Group Inc. is a late stage biopharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings.  Devonian Health Group Inc. was incorporated in 2013 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercial division, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSX Exchange (TSXv:GSD).

For more information, visit www.groupedevonian.com.

Forward Looking Statements

This press release contains forward-looking statements about Devonian’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate. Such risks and assumptions include, but are not limited to, Devonian’s ability to develop, manufacture, and successfully commercialize value-added pharmaceutical and cosmeceutical products, the availability of funds and resources to pursue R&D projects, the successful and timely completion of clinical studies, the ability of Devonian to take advantage of business opportunities in the pharmaceutical and cosmeceutical industries, uncertainties related to the regulatory process and general changes in economic conditions. You will find a more detailed assessment of the risks that could cause actual events or results to materially differ from our current expectations in Devonian’s prospectus dated April 21, 2017 under the heading “Risk Factors” related to Devonian’s business. As a result, we cannot guarantee that any forward-looking statement will materialize. We assume no obligation to update any forward-looking statement even if new information becomes available, as a result of future events or for any other reason, unless required by applicable securities laws and regulations.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post Devonian signs a Binding Letter of Intent with Histapharm Inc. to extract and manufacture their proprietary botanical pharmaceutical product and to enter into a Strategic Partnership for the development of New Products appeared first on DEVONIAN HEALTH GROUP INC..

Devonian Health Group Announces the Formation of a Scientific Advisory Board with mandate to assist in the development of Cannabinoïds-based pharmaceutical products.

QUEBEC, April 10, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation”) (TSXV: GSD), a clinical stage botanical pharmaceutical corporation focused on developing a unique portfolio of botanical prescription drugs and cosmeceutical products, announced today that it has formed a Scientific Advisory Board comprised of experts in botany, chemistry, immunology, infectious diseases, drug discovery and development. This Scientific Advisory Board will assist Devonian’s Research and Development team in the development of cannabinoïds-based pharmaceutical drugs.

The appointees are Dr. Louis Flamand, PhD, MBA (Laval University), Dr. Suha Jabaji, PhD (McGill University), Prof. Francois Malouin, PhD (Université de Sherbrooke), and Dr. John Trant, PhD (University of Windsor).

“We are honored to welcome these leading Canadian experts to our new Scientific Advisory Board. The expertise they bring to our team will be invaluable in guiding us through the development of cannabinoids-based pharmaceutical drugs,” said Dr. André P. Boulet, PhD., President & CEO of Devonian.

“We believe that cannabinoids-based products could be developed as pharmaceutical drugs either under the normal drug development pathway, as New Chemical Entities (NCE) or under the Botanical Drug Regulation. Under the Botanical Drug Regulation, plant materials, algae, macroscopic fungi, or combinations thereof can be developed as a prescription drug¹. Such products benefit of the combined effects of the components called the ‘‘entourage effects’’. The botanical drug’s special features require consideration and adjustment during regulatory review process. The US-Food and Drug Administration (FDA) issued a Guidance for Industry-Botanical Drug Products¹ to take into consideration these features and to facilitate development of new prescription medicines from botanical sources. Devonian’s core strategy is to develop drugs, including cannabinoïds, within the Botanical Drug Regulatory pathway.,” added Dr Boulet.

The Corporation also announces the filing of an application in order to obtain a Cannabis Research Licence from Health Canada.

Dr Louis Flamand, PhD, MBA
Louis Flamand, PhD, MBA, is a full professor and chair of the department of microbiology-infectious-disease-immunology at the Faculty of medicine, Université Laval and senior researcher in the division of infectious and immune diseases at the CHU de Quebec research center-Université Laval. Before joining Laval university, Dr Flamand obtained his PhD in virology from the University of Montreal and post-doctoral training that the National Institutes of Health and at the Institute of Human Virology (Maryland, USA). He received his MBA in pharmaceutical management from Université Laval.  He is also member of the HHV-6 Foundation scientific advisory board since 2006. Dr Flamand has experience in pre-clinical development. Throughout his career, Dr Flamand has received several competitive scholarship awards and continuous funding support from several funding agencies for his work in virology. Dr Flamand is the author of more than 90 peer-reviewed publications and is lead Editor of the book “Human Herpesviruses HHV-6A, HHV-6B & HHV-7: Diagnosis and Clinical Management” 3rd edition.

Dr Suha Jabaji, Ph.D.
Dr Suha Jabaji, PhD. is a molecular plant pathologist. She obtained her PhD from the University of Waterloo, Ontario, Canada. At the rank of full Professor in Plant Science, McGill University, her scientific contributions are recognized at the national and international levels. She has published 90 plus-refereed scientific reports and delivered more than 200 scientific presentations at scientific conferences. The creativity, relevance, and significance of her research results impacting sustainable agriculture is recognized by invitations to speak in symposia and conference presentations at scientific meetings, and serving on national and international editorial boards and grant panels. Her research expertise focuses on functional genomics and metabolomics of plant fungal pathogens and beneficial microbes that boost the plant’s immune system against biotic and abiotic stress has attracted International researchers to spend time in her lab for training. Her research program is funded by provincial, federal grants as well as industrial collaborative grants and contracts. She has mentored more than 100  graduate and postgraduate students in the field of Plant-microbe interactions. Among her current research themes is the development of effective antimicrobials for the hemp and Cannabis industries, and understanding their mode of action in order to increase their efficiencies. Between 2005-2015, she was appointed as the Associate Dean of Research and Graduate Education of the Faculty of Agricultural and Environmental Sciences (FAES), McGill where she oversaw the research activities of more than 90 staff at FAES. She currently serves as Past-President of the International Rhizoctonia Subject Matter Committee whose mandate is to coordinate international effort towards effective communication among scientists working on the economic soilborne fungal pathogen Rhizoctonia and promote exchange of resources and ideas among scientists.

Prof François Malouin, PhD
François Malouin is professor (microbiology) at the Department of biology at the Faculty of sciences of Universite de Sherbrooke since 2000.  He is a microbiologist that has more than 30 years of academic and industrial experience in drug discovery for use in humans and food-producing animals.  Prof Malouin obtained a doctoral degree (Ph.D.) in Medical Sciences (Medical Microbiology) at the University of Calgary (1988) and did postdoctoral training in the anti-infective research group at Lilly Research Laboratories (Eli Lilly & Co., Indianapolis, USA) from 1988 to 1990.  Prof Malouin was also Assistant professor of microbiology at the Faculty of medicine of Université Laval in Quebec City where he had a Fellowship from the Medical Research Council of Canada (1990-1994). He was then recruited by biotechnology companies, first Microcide Pharmaceuticals, Inc., then a sister company, Iconix Pharmaceuticals, Inc. (Silicon Valley, California, USA) from 1994 to 2000, where he was Associate Director of technology development for the discovery of new therapeutic targets and antibiotics. He was also a co-founder of Ulysses Pharmaceuticals (Sherbrooke, QC).  Currently at U. de Sherbrooke, his research projects aim at exploiting virulence genes for the development of new antibiotics, vaccines and non-antibiotic alternatives for applications in human and animal health.  He is co-author of >100 scientific publications and co-inventor of more than 20 patents (delivered or pending). ). Prof. Malouin was a member and president of the institutional patent committee at Université de Sherbrooke from 2009 to 2017.

“Medicinal plants have been used for centuries for treating various types of illnesses including treatment of infectious diseases.  A richness of new chemical entities remains unexploited to this day and cannabinoid-rich products represent such an untapped source of bioactive phytomolecules to address the current crisis of antibiotic resistance”. Said Prof Malouin.

Dr John Trant, PhD
Dr. John Trant received his PhD from the University of Ottawa in 2012 in making antifreeze glycopeptides under the supervision of Dr. Robert Ben. After postdoctoral work with Dr. Tomas Hudlicky (natural product synthesis, Brock) and Dr. Elizabeth Gillies (polymer and nanoscience, Western) he began his own group at the University of Windsor in 2016. The Trant group is focused on bringing the tools of synthetic chemistry to bare on unsolved problems in biomedicine and materials science. The group has active research in molecular and microbiology, natural product and peptide synthesis, and computational chemistry and biochemistry. The group conducts interdisciplinary research with collaborators from around Canada and the World in drug development, analytical chemistry, computational chemistry as well as leading research programs in undergraduate research pedagogy, and laboratory safety. The group has attracted over $2 million in research and infrastructure funds in the first three years of the lab, and currently comprises seven post-doctoral fellows, five graduate students and thirty-one undergraduate researchers.

‘We are exceptionally excited to move forward in this collaboration with Devonian Health Group to advance the health of Canadians’. Said Dr Trant.

About Devonian
Devonian Health Group Inc. is a late stage botanical pharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings.  Devonian Health Group Inc. was incorporated in 2013 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercialization partner, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSXV Exchange (TSXv:GSD).

For more information, visit www.groupedevonian.com.

References

1. Botanical Drug Development, Guidance for Industry. U.S. Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER), December 2016.

Forward Looking Statements
This press release contains forward-looking statements about Devonian’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate. Such risks and assumptions include, but are not limited to, Devonian’s ability to develop, manufacture, and successfully commercialize value-added pharmaceutical and dermo-cosmeceutical products, the availability of funds and resources to pursue R&D projects, the successful and timely completion of clinical studies, the ability of Devonian to take advantage of business opportunities in the pharmaceutical and dermo-cosmeceutical industries, uncertainties related to the regulatory process and general changes in economic conditions. You will find a more detailed assessment of the risks that could cause actual events or results to materially differ from our current expectations in Devonian’s prospectus dated April 21^st, 2017 under the heading “Risk Factors” related to Devonian’s business. As a result, we cannot guarantee that any forward-looking statement will materialize. We assume no obligation to update any forward-looking statement even if new information becomes available, as a result of future events or for any other reason, unless required by applicable securities laws and regulations.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post Devonian Health Group Announces the Formation of a Scientific Advisory Board with mandate to assist in the development of Cannabinoïds-based pharmaceutical products appeared first on DEVONIAN HEALTH GROUP INC..

Devonian Health Group announces the publication of results of in vitro assessment of the antioxidant and UV protection properties of thylakoid extracts in Journal of Cosmetic Dermatology.

QUEBEC, April 8, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation”) (TSXV: GSD), a clinical stage botanical pharmaceutical corporation focused on developing a unique portfolio of botanical prescription drugs and cosmeceutical products, announced today that researchers have published results related to thylakoid extracts resulting from its R&D program.

Published in the peer-reviewed Journal of Cosmetic Dermatology¹ entitled, ‘‘Study of antioxidant properties of thylakoids and application in UV protection and repair of UV-induced damage’’ the article describes results from in vitro studies aiming at better understanding the mechanism of action of thylakoid extracts in relation to cosmeceutical applications.

Results showed that the thylakoid extracts were not cytotoxic to human THP-1 cells. Moreover, formulations comprised of 0.1% or 0.01% of thylakoids in combination with sunscreen provided a synergetic protection against UV exposure. When mixed with neutral cream, the thylakoid extracts were able to repair UV damages on tissue engineered human skin model. The authors concluded that molecules and enzymes present in thylakoid extracts are involved in protecting and restoring the harmful effects of UV exposure.

“We are very pleased to announce this scientific publication describing properties of thylakoid extracts developed by Devonian, of which R-Spinasome® forms the basis of our cosmeceutical line of products. Furthermore, the data from the in vitro studies supports that further research is needed in order to assess other potential cosmeceutical applications.” says Devonian’s President & CEO, Dr. Andre P. Boulet.

“We believe that science and skincare must intersect to deliver revolutionary advances in the exciting new world of botanical cosmeceuticals. R-Spinasome® forms the basis of our recently launched cosmeceutical line – Purgenesis™ Anti-Aging Care treatment. We are excited about this publication as it allows us to deliver science-based innovative skincare and clinically proven formulations chosen by experts as the daily skincare solution for women and men of all skin types.” says Sybil Dahan, President of Altius Healthcare Inc, Devonian’s Commercial division.

About R-Spinasome®

R-Spinasome® complex, is a photosynthetic cell extract composed of pigments, proteins and lipids extracted from green leaves. The structure of this complex is critical to its function as an anti-oxidant, enabling it to capture and dissipate noxious energy generated by Reactive Oxygen Species (ROS), returning the complex to a state where it is ready to undergo new activation cycles. It is this dynamism and capacity to regenerate that provides R-Spinasome® complex with unprecedented, long lasting anti-oxidant activity. In addition, an independent study reported that the photosynthetic cell extract protects against ultraviolet A (UVA) and ultraviolet B (UVB) damages. R-Spinasome® is patent-protected in Japan, Canada, United States and Europe (#JP 5952261; #CDN 2,699,6765; #US 13/261,472, #EUR 11 768 299.7).

About Purgenesis™ anti-aging treatment

Purgenesis™ Anti-aging treatment has three components: a day cream, a night cream and an eye cream. These creams contain R-Spinasome®, a complex that is an active structure with anti-oxidant properties. The structure of this complex is critical to its function as an anti-oxidant, enabling it to capture and dissipate noxious energy generated by Reactive Oxygen Species (ROS), returning the complex to a state where it is ready to undergo new activation cycles. It is this dynamism and capacity to regenerate that provides R-Spinasome® with unprecedented, long-lasting anti-oxidant activity. A clinical study involving 72 subjects (aged 35-72years) was conducted to evaluate the performance of Purgenesis™ Anti-aging product line compared with two other leading prestige brands over a 28-day period of use. The results indicate that Purgenesis™ Anti-aging line is significantly superior than leading prestige brands in terms of its anti-wrinkle, firmness and hydration effects. Purgenesis™ Anti-aging treatment is patent-protected in Japan, Canada, United States and Europe (#JP 5952261; #CDN 2,699,6765; #US 13/261,472, #EUR 11 768 299.7). The product has been recognized by the Canadian Dermatology Association’s Skin Health Program™.

For more details, visit : www.purgenesis.com

About Devonian

Devonian Health Group Inc. is a late stage botanical pharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings.  Devonian Health Group Inc. was incorporated in 2013 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercialization partner, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSXV Exchange (TSXv:GSD).

For more information, visit www.groupedevonian.com.

About Altius Healthcare Inc

Based in Concord, Ontario, Altius Healthcare is a specialty pharmaceutical company with a primary focus of acquiring and in-licensing safe and innovative medicines and healthcare products designed to help people of all ages live healthier lives. Altius then leverages its expertise in the commercialisation activities required to successfully launch and distribute these medicines in Canada. The team’s diverse experience and expertise draws from nearly 40 years of producing, importing, marketing and distributing branded and generic medicines.

For more information, visit www.altiushealthcare.ca

Reference

St-Pierre A, et al. Study of antioxidant properties of thylakoids and application in UV protection and repair of UV-induced damage. J Cosmet Dermatol. 2019; 1-12.

Forward Looking Statements

This press release contains forward-looking statements about Devonian’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate. Such risks and assumptions include, but are not limited to, Devonian’s ability to develop, manufacture, and successfully commercialize value-added pharmaceutical and dermo-cosmeceutical products, the availability of funds and resources to pursue R&D projects, the successful and timely completion of clinical studies, the ability of Devonian to take advantage of business opportunities in the pharmaceutical and dermo-cosmeceutical industries, uncertainties related to the regulatory process and general changes in economic conditions. You will find a more detailed assessment of the risks that could cause actual events or results to materially differ from our current expectations in Devonian’s prospectus dated April 21^st, 2017 under the heading “Risk Factors” related to Devonian’s business. As a result, we cannot guarantee that any forward-looking statement will materialize. We assume no obligation to update any forward-looking statement even if new information becomes available, as a result of future events or for any other reason, unless required by applicable securities laws and regulations.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post Devonian Health Group announces the publication of results of in vitro assessment of the antioxidant and UV protection properties of thylakoid extracts in Journal of Cosmetic Dermatology appeared first on DEVONIAN HEALTH GROUP INC..

Devonian Healthcare Group Reports Key Financial Results for Quarter Ended January 31, 2019

 Quebec, Quebec – April 2, 2019 – Devonian Health Group Inc. (“Devonian” or the “Corporation”) (TSXv: GSD), a clinical stage botanical pharmaceutical corporation focused on developing a unique portfolio of botanical prescription drugs and cosmeceutical products, today reported key results from operations for the quarter ended January 31, 2019.

Financial Highlights for the quarter ended January 31, 2019

• For the three-month period ending January 31, 2019, the Corporation recorded revenues of $3,354,684, amounting to $5,317,215 for the six-month period ending on the same date. The Corporation’s revenues are generated by the distribution of two pharmaceutical products, Cleo-35® and Pantoprazole Magnesium, through its subsidiary Altius Healthcare. For the same periods in the prior year, the Corporation recorded no income.

• During the quarter ending January 31, 2019, Research and Development expenses amounted to $95,240, and $316,313 for the six-month period ending the same date. These expenses are mainly attributable to the costs incurred for the clinical trial on Adult Atopic Dermatitis, the costs related to patents, as well as the related payroll assigned to this sector. Research and Development expenses of $277,276 and $533,705 were respectively incurred for the same periods in 2018. The decrease, compared to the corresponding 2018 periods is mainly due to the Research and Development tax credits recorded for a total of $191,773 in January 2019, as well as a reduction in extraction activities compared to 2018.
• For the three-month period ending January 31, 2019, the net loss amounted to $399,220 ($ 0.006 per share) and $1,055,805 ($ 0.016 per share) for the six-month period ending on the same date. For the same comparative periods ending January 31, 2018, the Corporation realized a net loss of $783,608 ($ 0.013 per share) and $1,427,486 ($0.024 per share). This increase in net income is mainly attributed to revenues from Distribution and lower Research and Development expenses, partially offset by higher General and Administrative expenses and Financial expenses incurred during the period ending January 31, 2019.

“We are very pleased with the financial results of our Commercial Division, Altius Healthcare Inc. Devonian acquired Altius on February 1^st, 2018, which includes the revenues from its existing product portfolio, namely Pantoprazole magnesium and Cléo-35®. Altius’ margins are in line with management expectations and partially offset some R&D expenses.’’ said Dr Andre P. Boulet, President and CEO of Devonian.

• All amounts referenced herein are in Canadian dollars.
• Unaudited financials for Q2-2019 can be found on SEDAR.

About Devonian

Devonian Health Group Inc. is a late stage botanical pharmaceutical corporation with novel therapeutic approaches to targeting unmet medical needs. Devonian’s core strategy is to develop prescription botanical drugs from plant materials and algae for the treatment of inflammatory-autoimmune diseases including but not limited to ulcerative colitis and atopic dermatitis. Based on a foundation of over 15 years of research, Devonian’s focus is further supported by a US-FDA set of regulatory guidelines favouring a more efficient drug development pathway for prescription botanical drug products over those of traditional prescription medicines. Devonian is also involved in the development of high-value cosmeceutical products leveraging the same proprietary approach employed with their pharmaceutical offerings.  Devonian Health Group Inc. was incorporated in 2013 and is headquartered in Québec, Canada where it owns a state-of-the art extraction facility with full traceability ‘from the seed to the pill’. Acquired in 2018, Altius Healthcare Inc., its commercialization partner, brings opportunities for further diversification and growth potential. Devonian is traded publicly on the TSX Exchange (TSXv: GSD).

For more information, visit www.groupedevonian.com

About Altius Healthcare Inc.

Based in Concord, Ontario, Altius Healthcare is a specialty pharmaceutical company with a primary focus of acquiring and in-licensing safe and innovative medicines and healthcare products designed to help people of all ages live healthier lives. Altius then leverages its expertise in the commercialisation activities required to successfully launch and distribute these medicines in Canada. The team’s diverse experience and expertise draws from nearly 40 years of producing, importing, marketing and distributing branded and generic medicines.

For more information, visit www.altiushealthcare.ca

 Forward Looking Statements

This press release contains forward-looking statements about Devonian’s objectives, strategies and businesses that involve risks and uncertainties. These statements are “forward-looking” because they are based on our current expectations about the markets we operate in and on various estimates and assumptions. Actual events or results may differ materially from those anticipated in these forward-looking statements if known or unknown risks affect our business, or if our estimates or assumptions turn out to be inaccurate. Such risks and assumptions include, but are not limited to, Devonian’s ability to develop, manufacture, and successfully commercialize value-added pharmaceutical and dermo-cosmeceutical products, the availability of funds and resources to pursue R&D projects, the successful and timely completion of clinical studies, the ability of Devonian to take advantage of business opportunities in the pharmaceutical and dermo-cosmeceutical industries, uncertainties related to the regulatory process and general changes in economic conditions. You will find a more detailed assessment of the risks that could cause actual events or results to materially differ from our current expectations in Devonian’s prospectus dated April 21, 2017 under the heading “Risk Factors” related to Devonian’s business. As a result, we cannot guarantee that any forward-looking statement will materialize. We assume no obligation to update any forward-looking statement even if new information becomes available, as a result of future events or for any other reason, unless required by applicable securities laws and regulations.

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

Contact:

Dr. André P. Boulet, PhD
President and Chief Executive Officer
Devonian Health Group Inc.
Telephone: (514) 248-7509
e-mail: apboulet@groupedevonian.com

The post Devonian Healthcare Group Reports Key Financial Results for Quarter Ended January 31, 2019 appeared first on DEVONIAN HEALTH GROUP INC..